Welcome to the Keller Lab

-using Drosophila to study neurodegeneration-


Neurodegeneration can be defined by the progressive loss of structure or function of neurons. Many devastating neurodegenerative diseases in humans affect motoneurons, or neurons which contact and signal muscle contractility. The Keller lab uses Drosophila as a model organism to investigate motoneuron degeneration at the neuromuscular junction of fruit fly larva. The overarching goal of the Keller lab is to understand the molecular mechanisms leading to neurodegeneration and to look for ways to suppress this process after it has been initiated.