de Lencastre Lab
Stress Response and Aging in the Worm
Naidoo D‡, Brennan R‡, and de Lencastre A (2023), Conservation and Targets of miR-71: A Systematic Review and Meta-Analysis, Noncoding RNA, Jul 26;9(4):41. Naidoo-NoncodingRNA-2023.pdf
Evans B†, Furlong H‡, and de Lencastre A (2021), Parkinson’s Disease and MicroRNAs - Lessons from Model Organisms and Human Studies, Experimental Gerontology, 2021; 155:111585. Evans-Experimental-Gerontology-2021.pdf
Inukai S‡, Pincus Z, de Lencastre A, and Slack FJ (2018), A microRNA feedback loop regulates global microRNA abundance during aging, RNA, 2018;24(2):159-172. Inukai-2018-RNA.pdf
de Lencastre A, Torello T, Keller L (2017), "An Investigative Graduate Laboratory Course for Teaching Modern DNA Techniques", Biochemistry and Molecular Biology Education, 2017; 45(4):351-359. de Lencastre et al, Biochemistry and Molecular Biology Education-2017.pdf
Basavaraju M‡ and de Lencastre A (2016), Alzheimer’s disease: presence and role of microRNAs, invited review in BioMolecular Concepts Journal, 2016;4:241-52. Basavaraju et al, Biomolecular Concepts-2015.pdf
de Lencastre A, and Slack FJ (2015), Discovery of Novel microRNAs in Aging Caenorhabditis elegans (Chapter on Immunosenescence, in Methods in Molecular Biology, 1343, 235–248, October, 2015). de_Lencastre-2015--Discovery_of_Novel_microRNA.pdf
Smith-Vikos T*, de Lencastre A*, Inukai S, Shlomchik M, Holtrup B, and Slack FJ (2014), MicroRNAs Mediate Dietary-Restriction- Induced Longevity through PHA-4/FOXA and SKN-1/Nrf Transcription Factors (Current Biology 24, 1–9, September, 2014).de Lencastre-Current Biology-ALL-2014.pdf
(* joint 1st authors).† - undergraduate student
‡ - graduate student or medical student
de Lencastre A and Slack FJ (2013), Dysregulation of piRNA expression in long-lived mutants and role on stress response and longevity in Caenorhabditis elegans, in preparation.
Inukai, S., de Lencastre, A., Turner M., and Slack, F.J. (2012) Novel microRNAs differentially expressed during aging in the mouse brain. PLoS One 7(7), e40028. Novel-miRNAs-Aging-Mouse-Brain-PLoS-ONE-2012.pdf
de Lencastre, A., Pincus, Z, Zhou, K., Kato M., Lee S.S., and Slack, F.J. (2010) MicroRNAs both promote and antagonize longevity in Caenorhabditis elegans, Curr Biol 20, 1-10. deLencastre-CurrentBiology-2010.pdf
Kato, M., de Lencastre, A., Pincus, Z., and Slack, F. J. (2009) Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development, Genome Biol 10, R54. miRNA-Expression-Deep-Sequencing-Genome-Biol-2009.pdf
de Lencastre, A., and Pyle, A. M. (2008) Three essential and conserved regions of the group II intron are proximal to the 5'-splice site, RNA 14, 11-24. deLencastre-RNA-2008.pdf
de Lencastre, A., Hamill, S., and Pyle, A. M. (2005) A single active-site region for a group II intron, Nat Struct Mol Biol 12, 626-627. deLencastre-NSMB-2005.pdf
Boudvillain, M., de Lencastre, A., and Pyle, A. M. (2000) A tertiary interaction that links active-site domains to the 5'splice site of a group II intron, Nature 406, 315-318. deLencastre-Nature-2000.pdf
Armstrong, N., de Lencastre, A., and Gouaux, E. (1999) A new protein folding screen: application to the ligand binding domains of a glutamate and kainate receptor and to lysozyme and carbonic anhydrase, Protein Sci 8, 1475-1483. Protein-Folding-Screen-Protein-Sci-1999.pdf
Roberts, R. B., de Lencastre, A., Eisner, W., Severina, E. P., Shopsin, B., Kreiswirth, B. N., and Tomasz, A. (1998) Molecular epidemiology of methicillin-resistant Staphylococcus aureus in 12 New York hospitals. MRSA Collaborative Study Group, J. Infect. Dis 178, 164-171.
de Lencastre, H., de Lencastre, A., and Tomasz, A. (1996) Methicillin-resistant Staphylococcus aureus isolates recovered from a New York City hospital: analysis by molecular fingerprinting techniques, J. Clin. Microbiol 34, 2121-2124.